The development of DNA DNA vaccine reduces the toxic proteins associated with Alzheimer's





Washington –


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Wednesday, November 21, 2018 – 11:23 p
| Last update:
Wednesday, November 21, 2018 – 11:23 p

Washington (Reuters) – A team of US. It. Scientists developed a vaccine data that was tested on rats that helped prevent the accumulation of both types of toxic proteins linked to the Alzheimer's disease, and could prevent the clinical trial.

A new study by the Peter O. Donnell Institute, in collaboration with the University of Texas Southwestern Medical Center, shows that the vaccine, which is delivered by the skin, stimulates the immune response to reducing the accumulation of harmful Tao proteins, amyloid , "Without causing heavy brain swelling due to pre-treatment of the antibody in some patients.

"This study culminates in a decade of research that has repeatedly shown that this vaccine can be targeted effectively and safely in animal models that are thought to cause disease," said Dr. Roger Rosenberg, established director of the Alzheimer's Center of the University of Utah. Alzheimer's "and expressed his belief in the approach of scientists to develop clinical tests on humans.

The study, published in the Journal of Alzheimer's Research and Treatment, explains how the vaccine, which contains the DNA coding of a part of the AMOLEOID beta, also reduces the accumulation of the protein among the most susceptible to Alzheimer's disease, as well as Making the vaccine in a different immune response may be safe for humans, and two previous studies have shown similar immune responses in rabbits and monkeys.

The vaccine comes in a short list of promising antibody treatments that aim to protect both types of proteins that kill brain cells, while circulating in blood plasma and intralines on the Alzheimer's scientists.

The latest study showed that the vaccine caused a 40% reduction in the amoleoid beta plaque and a 50% reduction in Tau protein without any negative response.


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