The genes of this animal produce tumor regression in humans and other mammals



A group of biologists discovered genes and mutations that seem to be involved in these Regression of cancerous tumors In the so-called Tasmanian Devils (sarcophilus harshii), a marginal native to South Autralia, reported the genomic genome biology and evolution.

Research can play a key role in elucidating the causes of a recurrent facial tumor on the animals. There is a contagious form of cancer that affects both females and males of the species and what determines a 100% mortality At a time of Between 12-18 months.

The scholar scientists will help drastically reduce the number of deaths and may have "implications for Treat human cancer And other mammals, "said the collective biologist Mark Margers, who stated that" some of the genes that have been attributed to the regression of tumors in Tasmanian devils They also exist in humans"

The experiment

The examination of the question is determined by an interesting observation: some specimens with facial tumors did not die and after a few months their tumors They disappeared. The researchers sequence the genomes of seven Tasmanian devils that experienced the tumor regression and the three did not.

The results revealed that the animals whose tumors have decreased has three highly differentiated genomic regions, including multi-genes that are related to the immune response and also to The risk of cancer In humans and other mammals. According to the scientists, this is the "first step towards the characterization of the genetic basis of the tumor regression trait".

Since the 1990's, this particular contagious disease has marked the population of the demons, carnivorous marchals whose habitat is concentrated on the island of Tasmania. The ailment is to form tumor in the mouth and in their environment, which hinder feeding Or even prevent it, Causing death Of the animal the disease is spread by direct transmission of living cells of cancer, by bites that are inflicted on each other in the face during feeding and matting processes.


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