First baby born after uterus transplant of deceased donor: case study



In what is believed to be a world first, a woman in Brazil gave birth to a healthy baby girl after receiving an uterine transplant from a deceased donor.

Researchers say the case study, including Tuesday in the Lancet, shows that such transplants of continued dancers are feasible and may increase women's vulnerability to uterine infertility.

The 32-year-old woman who signed the transplant in September, 2016, was brought without an uterus due to Mayro-Rokitanski-Kister-Hauser (MRKH) syndrome that affects the reproductive system.

The donor is a 45-year-old woman who has three former pregnancies and died of a bleeding caused by bleeding on the surface of the brain.

The uterus transplant surgery, a first in Latin America, took more than 10 hours to complete. The recipient tolerated the transplant relatively well thanks to immunosuppression drugs, other treatments and continuous monitoring.

The recipient has her for a period of 37 days after the uterine transplant, and still has regular cycles. Seven months after the transplant, the fertilized eggs are implanted in the uterus, resulting in pregnancy.

There were no major issues during pregnancy and no selection of organic rejection. The baby girl is born by Kesarean section on December 15, 2017, at 35 weeks of gestation. The healthy infant weighs six pounds at birth, and continues to develop normally.

The donated uterus was removed during the C-section and the woman's wound healed well, the researchers say.

They say that 10 other uterus transplants of deceased donors are done in the US. There is Turkey, Turkey and Czech Republic, but none of them has resulted in live birth.

"The use of deceased donors can greatly extend the access to this treatment, and our results provide proof-of-concept for a new option for women with uterine infertility," said Danny Ejenzberg, a gynecologist in São Paulo, which conducted the research, saying: In a news release.

He told live uterus dancers are rare and typically suitable family members or close friends of women seeking the transplant.

"The numbers of people who are willing to give ovate to their own deaths are much greater than those of donors of life, offering a lot more potential donors," he said.

The first birthday of an uterus transplant found in 2013 in Sweden, where a total of eight children were born thanks to transplants of live donors.

So far, there are 39 uterine transplants from live donors around the world, resulting in 11 births.

The authors of the Lancet paper note that the uterus transplants involve major surgery and high doses of immunosuppression drugs, and recipients need to be healthy to avoid complications during or after the procedure.


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