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Reproducts with the kind permission of Dr. Merkola.
By Dr. Mercola
Tetrahydrosanabinol (THC), Compound responsible for Marijuana's psychoactive effect, may offer hope for Alzheimer's treatment, at least according to a study on mice. Rodents with a disease similar to Alzheimer's gave a synthetic form of THC, which resulted in less lost brain cells, 20 percent less sticky plaques in the brain (which are linked to Alzheimer's) and a boost in memory.
In fact, alumner's mice given THC has also sound memory tests as well as mice, while those given a placebo lost some of their memory. 2 The study was presented in the Society for Neuroscience Meeting in San Diego, California, and has not yet been published, but it raises hope that a cannabis-based treatment may prove to be therapeutic for Alzheimer's.
THC improves memory in Alzheimer's mice
The study is interesting in finding THC – but not cannabidiol (CBD) – to be beneficial to memory function and neuron loss in mice with Alzheimer's. Cannabidol is the non-psychiatric component of cannabis, which has already found many benefits for pain relief, seizures and other health conditions.
Cannabinoids interact with your body by way of common event cananobinoid receptors embedded in cell membranes over your body. There are cannabinoid receptors in your brain, lungs, liver, kidneys, immune system and more; The therapeutic (and psychoactive) properties of Marijuana occur when a cannabinoid activates a cannabinoid recipe.
Your body also has an inherent event endocanabanoids similar to THC that stimulates your cannabinoid receptors and produces a variety of important physiological processes.
So, your body is actually hard-wired to respond to Cannabinoids through this unique Cannabinoid receptor system. It's likely that both THC and CABADDiol exert their effects through your body's endocrine system. According to the researchers: 3
"Endocannabinoid signaling is demonstrated to be involved in many processes, including brain development, memory formation, motor control, neurinflammation, exitotoxicity and oxidative stress.
In addition, some in Vitro studies showed that Cannabinoids reduce β [amyloid beta]Introduces neurotoxicity and sells death and facilitates neurogenesis. It can also be seen that cannabinoids stimulate the removal of intrauralurinal Aβ in vitro.
… Cannabinoid-Treatment in … Mice show the potential of the endosacnabinoid system as a therapeutic goal in Alzheimer's disease influencing the molecular signature and improving memory deficits. Our findings reinforce a cannabis-based drug as a potential ad [Alzheimer’s disease] Therapy. "
THQ may reverse brain aging
Researchers from the featured study warn that people should not take the results to mean they should light up in order to preserve their brain well. When given GIS, they actually had difficulty in teaching. However, previous research on mice also found THC to be beneficial to brain health.
One such study, published in Nature Medicine, found that a low dose of THC reversed the age-related decline in cognitive performance of mice 12 and 18 months.4. The dose is small enough to avoid any psychoactive effects, yet powerful enough to reverse the loss of performance in the old animals (mice typically 2 years old).
Further, gene activity and molecular profile in the brain tissue of THC-treated mice were that of much younger animals. Especially, neurons in the Hippocampus have grown more symptomatic spines – contacts are available for communication between neurons.
Further research has also shown that the brain times are much faster in mice that do not have functional receptors for THC, suggesting THC may be involved in the regulation of the aging process.5 The next logical step would be to test Marijuana and its compounds in people With Alzheimer's, however, the political red tape is holding up the scientific process.
The reform of NPR, Cannabis researcher Jamie Rösterman, an Associate Professor of Psychology at the University of Illinois in Chicago, explains, "There are only no venues to do it." NPR continues, "Getting approval for any study involving people and compounds to Marijuana is" very difficult, "she said, despite the fact that the drug is now legal in many countries." 6
After Cannabis therapies are in the forefront of neurology, according to researchers writing in front of Integra Neuroscience, and because they work through multiple mechanisms, it may be useful not only for Alzheimer but also for Parkinson disease, brain tumors, epilepsy And traumatic brain injury. They indicated: 7
"The internal palpharmaceutical properties of cannabis botanicals offer different advantages over the current single-purpose pharmaceutical model and portends to revolutionize neurological treatment into a new fact of effective intervention and even preventative treatment."
What else is medical Marijuana good for?
Cannabinoid receptors play an important role in many body processes, including metabolic regulation, cravings, pain, anxiety, boost growth and immune function. "Medical Marijuana" refers to the use of the whole, unprocessed marijuana plant or its extracts for medicinal purposes. Through traditional plant breeding techniques and seed exchanges, growers have started to produce cannabis plants that have higher levels of CBD and lower levels of THC for medical use.
Since the 2018 election, which resulted in several years satisfied various forms of marijuana, medical cannabis is now legal in 33 US dollars. It. However, recruitment is legal in 10 states and Washington, DC8 most of the areas where medical cannabis is legal only the use of safe medical constitution only, and some leave CBD oils or pills only. What are people using it for? Pain and anxiety are highly utilized, but it is also potent for its use as a cancer treatment.
For example, Harvard researchers found THC cats tumor growth in lung cancer, while reducing their ability to spread. Even in cases of glyoblastoma, one of the deadliest types of cancer, Cannabinoids may help, as they have been shown to inhibit the invasion of glyoblastoma tumors and improve survival of glyoblastoma patients.10 In addition, Cannabinoids have shown pledge for a variety of medical Uses, including: 11
- Multiple sclerosis
- Anorexia
- Irritable bowel syndrome
- Huntington's disease
- Addiction
- Eye diseases
- Chemotherapy-related nausea and vomiting
- Inflammatory and neuropathic pain
- Post-traumatic stress disorder
- Anxiety disorders
Interestingly, it's likely that both TC and CBD may have a beneficial role in health. One even found that CBD could buffer some of the psychoactive effects of THC and the two compounds could offer greater therapeutic results when administered together as alone.
If you're considering the use of medical marijuana, and you live in a state where it is legal, you can get a medical cannabis card from your doctor, then join a team that is a group of patients Which can grow and share cannabis Medicines with each other. By signing up as a member, you get the right to grow and share your medicine.
There are different ways to carry medical marijuana, ranging from inhalation, vaporization and smoking to sublinchal (under the tongue), oral injection and topically. The best way to do this is to depend on your medical needs and thus work with an experienced physician to determine the best route of administration and dosage.
Remember, though medical marijuana may seem like a new or trendy treatment, its medical properties have been valued for thousands of years, including Traditional Chinese Medicine, India, and ancient Egypt, Persians and Greeks.
Coffee: Another Natural Compound That Benefits Alzheimer's
Along with Marijuana, many other natural substances may also contain properties that inhibit Alzheimer's, and coffee is no exception. "Coffee consumption is correlated with a decreased risk of developing Alzheimer's disease (AD) and Parkinson's disease (PD), but the mechanism by which coffee could provide neuroprotection in humans is not fully understood," explains researchers.
It has previously been suggested that the caffeine in coffee may be responsible for many of its beneficial effects, but a new study has shown a similar benefit to the brain between both caffeinated and disinfectant varieties. The distinguishing factor was the type of roast, with dark roast coming out on top.
A compound called phenylindane is formed when coffee beans are roasted, with higher quantities found in darker roast. Phenylindane is also neuroprotective, as it inhibits amyloid-beta and tau aggregation, both of which are implicated in Alzheimer's. Researchers continue to look further at whether phenylindanes were able to enter the bloodstream and cross the blood-brain barrier.
Also similar to Marijuana, coffee consumption is associated with lower risk of glymoma brain tumor, such as people in the top category of coffee consumption are 91 percent less likely to develop glyoum compared to those in the bottom categories .14
Drinking one-two cups of coffee daily is also shown to lower your risk of Alzheimer's disease and other forms of dementia, cognitive decline and cognitive impairment compared to less than one cup.
Top Tips for Lowering Your Alzheimer's Risk
Alzheimer's disease has grown to be one of the most urgent and tragic public health issues to make the US. It. With the number of people affected expected to triple by 2050, the Alzheimer's Association estimates that by mid-sentence someone in the US. It. Will develop Alzheimer's disease every 33 seconds. 16
Medical Marijuana could one day prove to be a useful tool for Alzheimer's Prevention and Treatment, but it is not yet widely available for most people. Many other strategies that get to the root of the disease are now available, but, as exercise to increase brain-derived neurotropic factor (BDNF), stress reduction, optimizing your sleep, which is crucial for cognitive function, and nutritional support.
Important nutrients include animal-based omega-3 fats, magnesium, vitamin D and fiber. For example, seniors with severe vitamin D deficiency can raise the risk of diamania by 125 percent, and vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer's disease .17 Have your levels tested and maintain a blood level 60-80ng / ml annually.
As for omega-3, high intake of the Omega-3 fats of EPA and DHA help prevent cell damage caused by Alzheimer's disease, thereby slowing down its progression and lowering your risk of developing the disorder. Ideally, get a Omega-3 Index Test done once a year to make sure you are in a healthy range. Your Omega-3 index should be above 8 percent and your omega 6-to–3 ratio between 0.5 and 3.0.
I also recommend a cyclical or targeted ketogenic diet to help you optimize your health by converting burning carbohydrates for energy to burn fat as your primary source of fuel. You can learn more about the approach to improving your mitothhdrial function, which is also in the heart of Alzheimer's disease, in my book, "Fat for Fuel."
One of the most common side effects of being a sugar-burner is that you are smashed with insulin and lipton resistance, which is the root of most chronic illness. Intermittent fasting is a powerful powerful tool to jump your body in remembering how to burn fat and repair insulin / leptin resistance. Together, the lifestyle strategies remain your best defense to avoid dementia and keep your brain strong.
For more information, you must choose a copy of "The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline" by Dr. Dale Bredesan, director of Neurodegenerative Disease Research at the University of California, Los Angeles (UCLA) School Medicine. It is packaged with tools for both prevention and treatment.
| This article was brought to you by Dr. Mercola. Founder of the World's # 1 Natural Health Site, he gives you the low-down on cholesterol. Discover what you really need cholesterol in this free release. |
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Sources and references
1, 3 Neuroscience 2018, November 6, 2018
2, 6 NPR November 7, 2018
4 Nature Medicine May 8, 2017
5 Act Aging May 9, 2017
7 Front Integral Neurosci. 2018 18th October 12:51.
8 CBS News November 20, 2018
9 Signed 2008 Jan 10, 27 (3): 339-46
10 Front time Neurossi. 2018 May 16; 11: 159.
11 Drugs. November 2018, 78 (16): 1665-1703.
12 Front Farmacol. 2017 Feb 3; 8:20.
13 Front Neurossi. 2018 October 12; 12: 735.
14 EUR jutr. 2017 9 November.
15 Clean neutr. June 2017; 36 (3): 730-736.
16 Alzheimer's Association, 2016 Alzheimer's disease facts and figures
17th Neurology August 6, 2014
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