A preocupação existiu desde o começo. Descerto que o Crispr surgiu, si se anos, e revista científicas e internazionale órgãos ponderam: podemos editar o DNA humano? Nos estamos falando de uma molécula que existe há milhares, muitos milhares de anos. Are you serious about limiting genetic engineering? É uma questão ética complexa.
By the way, the DNA scan is simple and simple. Oh, how long can you, like a revolution, like the prestigious "science" science curriculum for the sake of your capas. Cough bees are resistant to HIV, as well as Chinese medicine. Podemos editar, na verdade, o materiel genético de praktischam serqual vivo. As expectativas giram em torno da cura de doenças importantes, como al Alzheimer e o câncer.
Entenda o que o Crispr
The culprits have been tested for the benefit of 2012, the "bombing" in 2015. It is used to alter the genius of human embryos, extramuscular currents, and non-viral substances, antigenic agents and resistant tritters.
Tudo isso com a ajuda de uma enzima presente la sistema de defesa das bactérias. Os pesquisadores usam a Cas9 junto com a RNA "guia" para "recortar" in part que que interesse est DNA.
Entenda o Crispr – Photo: Betta Jaworski / G1
No meio disso tudo, o Crisprito citado como uma chance para um Futuro Nobel. In the quest for the resolution of the decision – the decree has been passed since the beginning of this year: three cents, thousands and a half, have been sent to patent for justice in the United States.
A patent de milionária, avaliada em milhões de dólares. The lado, many more frequent ceremonies to concede in Nobel: a microbiologist Emmanuelle Charpentier, the Max Planck Institute; e bioquímica Jennifer Doudna, University of Califórnia, in Berkeley. Do out, Feng Zhang, do Instituto Broad, the University of Technology at Universidade Harvard and MIT.
The fevere of 2017, Zhang venceu a batalha. You can see how the rules are used in the workplace.
Feng Zhang, do Instituto Broad – Photo: Stan Grazier / Instituto Broad
O pesquisador chinês He Jiankui has said that the primitive genetic drugs have been edited by the world. São and Menina gêmeas – Lulu e Nana – nascidas neste mês.
There is no confirmation of the censorship of the He. There are no artifacts censors in revival, not prestigious, but despicable. Não divulgou o nome dos envolvidos.
The scientist scientist He Jiankui affirms to cure the earliest genetic drugs in the world. – Photo: Mark Schiefelbein (AP)
Voltamos início do texto: podemos editar uma molécula que demorou milhões de anos para chegar onde está?
Independent items because of this, you have a lot of longevity.
In August 2017, the "Nature" published the prime example of genetic defects in human embryos to evolve hereditary cardiac condition. A pesquisa gerou embriões saudáveis, that sem edição genética teriam desenvolvido a cardiomiopatia miotrífica – doença that dificulta o bombeamento do sangue pelo coração.
In April 2016, the Cell Reports period announced that the precision of the technique was designed to evolve the vulnerability of AIDS, with its maximum capacitance. In addition, in 2017, the "Molecular Therapy" published the cientists of the Universidade Temple, or Filadelfia, to educate the code and evade the continuous vibes and replicas of animations.
The state-of-the-art education of human genes has been edited with Criminal on August 2016. The time of the Sichuan University has introduced a modification of empathy to a species of aggressive trafficking – a protective genetic offspring with a spell response DNA is justified and it is used to proliferate.
Embryo's human rights have changed the way for a new genetic engineering scheme, different from CRISPR (using our image) – Photo: OHSU
Our United States, cientistas human human traits in transplant realizations. Issues in the following areas: First, the specialist removes the gene from an embryo of the recipient's fertilizers and has become a member of the disintegration of parcels. Deposit, as cellulose-tronco human is injected into the animal's embryo. As it is, the human body is developing into porcine and deposits that can be used to prevent surgery.
To consolidate the use and legitimization of implementing internationally, or even those of the countries that have attracted the pessimisms: United States and China. Assim, the cientist's point of departure is with securities and the form of ethics about the assignment.
O G1 Most of the anunciations of China have been edited on the DNA of the beef that make protest cientists in the world. Segundo especialistas, ele feriu a ética, as leis, a segurança, e tem consequências imprevisíveis. At the University of the University of He Jiankui is manifested as saying that he was investigating the case. Segundo a instituição, o caso é "uma violação grave de ética e dos padrões acadêmicos".
Our United States, and the FDA, "Anvisa" in the country, as well as the development of pescus algum. In March this year, the agenda interrupted the first human test with Crispr.
He states the United States, just, that genetic engineering does not allow human application, excerpts from laboratories, interference with life or perpetuation. In China, the human brain is specifically designed to provide gene expression.
A preoccupation of the American regulatory frameworks: a "Nature Biotechnology" questions the Crisprice precision and the laboratory experiments using the camundongs and human resources that a technique causes frequent elements of extensive genetic mutations.
The acord with the pesquisadores, as "mudanças the DNA for the subjects of antiretroviral serum".
In the context of the question about the potential "salvador" of Crispr published in June this year, "Nature Medicine": the use of technical resources to reduce the risk of collapse. Segundo os cientistas, a edição teria uma tiencência de selecionar células sem uma proteína importante para barrar malacismos cancerígenos.
E, no meio disso tudo, os ormas como a FDA, que permitamente determinar uma barreira para todas as pesquisas, como com a destina estilo "ovo ou galinha": devemos continuar com pesquisas para entender de riscos e determinaran um limite, ou devemos Determination to Limite and Continuous Pesquisas of Risk?
This is the answer that we have just discussed with our previous questions, including the fact that the bees do not have to worry about it.