December 4, 2018 – 18:31
A team of researchers managed to restore hair on affected skin after activating a cell signaling pathway.
No more bald? A team of researchers led by Scientists from the School of Medicine at the University of New York to identify molecular signaling pathways that prevent the growth of hair on injured skin, which could help in the search for better drugs to reverse latitude, reported GEN.
In their study, scientists activated the signaling pathway of Sonic Hedgehog (SHH) used by cells to communicate with each other. It is known that the pathway is very active in the early stages of human growth in the uterus, when hair follicles form, but stagnates in injured skin in healthy adults.
"We assert that the activation of the SHH pathway regenerates a regenerative dermal niche, called 'Dermal Papilla', which is necessary and sufficient for the neocolysis of hair follicles (hp)," the authors wrote in their work.
"Our findings show that the stimulation of fibroblast by the sonic hedgehog pathways can activate hair growth no earlier seen in wound healing", said the chief investigator, Mayumi Ioo, a professor at the Department of Dermatology at the Langone Health Center associated with the University From New York.
The researcher said she hopes that the work will help you achieve her main objective, which is to make the adult skin return to its embryonic state so that it can produce new hair follicles not only in the case of injured skin, but also in People who continue to bite through aging.